PROJECTS

Principal Investigator

2017-2020

Development of novel multifunctional and targeted nanocarriers for the treatment of breast cancer and investigation of in vitro and in vivo efficiencies

The Scientific and Research Council of Turkey

(1003)

Researcher

2017-2020

Development of Breast Cancer Targeted, More Stable, Double-Moiety pH-Sensitive, Drug-Conjugated Multifunctional Micelle-Based Nanocarriers and Investigation of Their in vitro Efficiency

The Scientific and Research Council of Turkey

(1001)

Researcher

2018-2020

Cytotoxic Effects of New Benzimidazol Metal Complexes on Peritoneal Implantation of Lung Cancer; An In vivo Experimental Study

Inonu University

Advisor

2018-2020

Determination of Histone Deacetilase Inhibitors on PTEN/PI3K/AKT/mTOR signaling pathway and development of Cholangiocarcinoma at the molecular level

The Scientific and Research Council of Turkey

Researcher

2017-2020

Investigation of Effects of Gene Editing of Bcr/Abl1 and SK-1 genes by CRISPR technology in chronic myeloid leukemia cells

Erciyes University

Prinicipal Investigator

2015-2016

A Novel Therapeutic Approach for Ph+ Acute Lymphoblastic Leukemia; Targeting Sphingosine Kinase Signaling Pathway

Eczacibasi Holding

Prinicipal Investigator

2015-2016

Expression Levels of JAK-STAT Signaling Pathway Genes and Their Effects on Clinical Outcome in Chronic Myeloid Leukemia Patients

Guven Hospital

Advisor

2016-2018

Therapeutic Potentials of Resveratrol on Ph+ Acute Lymphoblastic Leukemia and The Roles of Ceramide Metabolism in Resveratrol Induced Apoptosis

The Scientific and Research Council of Turkey

Prinicipal Investigator

2012-2015

Expression and Protein Levels of Bioactive Sphingolipid Genes in Newly Diagnosed and Drug-Resistant Chronic Myeloid Leukemia Patients and Their Impact on the Clinical Progress

The Scientific and Research Council of Turkey

Advisor

2016-2018

Synthesis of Poly(cations) with Varying Molecular Architectures via RAFT Polymerization and In vitro Investigation as siRNA Carriers

The Scientific and Research Council of Turkey

Researcher

2015-2016

Determination of Effects of Apigenin on Chronic Myeloid Leukemia Stem Cells; Mechanistic Approach

Erciyes University

Researcher

2015-2016

Investigation of Cytotoxic Effects of Quercetin on CML Stem Cells at Molecular Level

Erciyes University

Prinicipal Investigator

2011-2012

Apoptotic Effects of CAPE and Gossypol on Acute Lymphocytic Leukemia Cells

Turkish Society of Hematology

Prinicipal Investigator

2010-2013

Therapeutic Potentials of Bioactive Sphingolipids in Chronic Myeloid Leukemia

Turkish Academy of Sciences

Advisor

2013-2015

Development of PEG-peptide conjugate anticancer drug carrier systems responding pH

The Scientific and Research Council of Turkey

Researcher

2014-2015

Treatment of HT-29 and HCT-116 colon cancer cell lines with mesenhcymal stem cells

Istanbul University

Advisor

2012-2014

Effect of Mesenchymal Stem Cell on Experimental Bronchiolitis Obliterans Therapy

The Scientific and Research Council of Turkey

Assistant Researcher

2012-2013

Genome Wide Expression Levels of mRNA and miRNA in Response to anti-STAT5A in Parental and Imatinib Resistant Human K562 Chronic Myeloid Leukemia Cells

Ege University

Assistant Researcher

2012-2013

Determination of Possible Synergistic Apoptotic Effects of Dexamethasone With Foxm1 Inhibitor, Siomycin A, in Acute Lymphocytic Leukemia

Dokuz Eylul University

Assistant Researcher

2012-2013

Effects of Nilotinib on Endothelial Cell Function

Dokuz Eylul University

Assistant Researcher

2012-2013

Evaluation The Effects of Gene Therapy, Ultrasound and Photobiomodulation on Orthodontically Induced Root Resorption

Erciyes University

Assistant Researcher

2012-2014

The roles of Mesenchymal Stem Cells on Experimental Allergic Rinit Therapy

Dokuz Eylul University

Prinicipal Investigator

2009-2011

The Involvement of Ceramide Metabolizing Genes and Their Products in Docetaxel Induced Apoptosis in Human Androgen Resistant Prostate Cancer Cells

The Scientific and Research Council of Turkey

Prinicipal Investigator

2008-2011

Multidrug Resistance Mechanisms In Chronic Myeloid Leukemia Cells Treated With Molecular Targeting Agents, Activated Signal Transduction Pathways And Reversal Of Resistance

The Scientific and Research Council of Turkey

Prinicipal Investigator

2008-2010

Induced Cancer Signalling Pathways, Activated Cell Death Mechanisms and the roles of Ceramide Metabolising Genes on These Mechanisms in Acute and Chronic Myeloid Leukemia Cells Exposed to Resveratrol

Turkish Society of Hematology

Prinicipal Investigator

2008-2010

The Effects of Ceramide Metabolism Genes On Apoptotic Pathways Induced By Different Anticancer Agents in Breast Cancer

Turkish Association for Cancer Research and Control

Assistant Researcher

2008-2011

Redox regulation of human p53 tumor suppressor gene activity

European Union, COST Action

Assistant Researcher

2010-2012

Monte Carlo Techniques for Biological and Chemical Reactions

TUBITAK

Turkey-Italy Bilateral Project

Assistant Researcher

2009-2011

Distraction Osteogenesis by the help of stem cells obtained from lipid tissues; An experimental study in Rabbit Tibia

Dokuz Eylul University

Prinicipal Investigator

2008-2009

Expression Analyses of Apoptotic and Drug Resistance Genes in STI571 applied parental and resistant K562 Cells

Izmir Institute of Technology

Assistant Researcher

2006-2008

Investigations and reversal of multidrug resistance mechanisms by molecular approaches in different cell lines

The Scientific and Research Council of Turkey

Assistant Researcher

2004- 2006

Investigations of Multiple Drug Resistance Mechanisms in Imatinib Mesylate Applied Chronic Myeloid Cell Lines

Middle East Technical University

Assistant Researcher

2000-2004

Investigations of Resistance Mechanisms Against Anticancer Drugs in breast Cancer and Drug Targeting

State Planning Organization

Assistant Researcher

(2000-2002)

Etermination of Expression Levels of MDR1 Gene in Blood

Middle East Technical University