PROJECTS
Researcher
2021-2023
Determination of Therapeutic Potential of Luteolin on Philadelphia Chromosome Negative Akut Lymphoblastik Leukemia (ALL) Cells
Izmir Institute of Technology
Researcher
2021-2022
Determination of Effects of Luteolin on Philadelphia Chromosome Negative Akut Lymphoblastik Leukemia (ALL) Cells by FTIR
Izmir Institute of Technology
Researcher
2020-2021
Development of STR Analysis Kit
The Scientific and Research Council of Turkey
Principal Investigator
2020-2021
Apoptotic Effects of Nilotinib, a Tyrosine Kinase Inhibitor, on Her2 Positive Breast Cells and Its Use in Combination Therapy
Izmir Institute of Technology
Principal Investigator
2019-2020
Determination of Effects of Second Generation Tyrosine Kinase Inhibitors and Sphingosine Kinase Inhibitor on Human Telomerase Enzyme Activity (hTERT) in Philadelphia Chromosome Positive Akut Lymphoblastik Leukemia Cells
Izmir Institute of Technology
Principal Investigator
2019-2020
Determination of Therapeutic Potential of Luteolin on Philadelphia Chromosome Positive Acute Lymphoblastik Leukemia (ALL) Cells and the Roles of Bioactive Sphinolipid Genes
The Scientific and Research Council of Turkey
Principal Investigator
2017-2020
Development of novel multifunctional and targeted nanocarriers for the treatment of breast cancer and investigation of in vitro and in vivo efficiencies
The Scientific and Research Council of Turkey
Researcher
2017-2020
Development of Breast Cancer Targeted, More Stable, Double-Moiety pH-Sensitive, Drug-Conjugated Multifunctional Micelle-Based Nanocarriers and Investigation of Their in vitro Efficiency
The Scientific and Research Council of Turkey
Researcher
2018-2020
Cytotoxic Effects of New Benzimidazol Metal Complexes on Peritoneal Implantation of Lung Cancer; An In vivo Experimental Study
Inonu University
Advisor
2018-2020
Determination of Histone Deacetilase Inhibitors on PTEN/PI3K/AKT/mTOR signaling pathway and development of Cholangiocarcinoma at the molecular level
The Scientific and Research Council of Turkey
Researcher
2017-2020
Investigation of Effects of Gene Editing of Bcr/Abl1 and SK-1 genes by CRISPR technology in chronic myeloid leukemia cells
Erciyes University
Principal Investigator
2015-2016
A Novel Therapeutic Approach for Ph+ Acute Lymphoblastic Leukemia; Targeting Sphingosine Kinase Signaling Pathway
Eczacibasi Holding
Principal Investigator
2015-2016
Expression Levels of JAK-STAT Signaling Pathway Genes and Their Effects on Clinical Outcome in Chronic Myeloid Leukemia Patients
Guven Hospital
Advisor
2016-2018
Therapeutic Potentials of Resveratrol on Ph+ Acute Lymphoblastic Leukemia and The Roles of Ceramide Metabolism in Resveratrol Induced Apoptosis
The Scientific and Research Council of Turkey
Principal Investigator
2012-2015
Expression and Protein Levels of Bioactive Sphingolipid Genes in Newly Diagnosed and Drug-Resistant Chronic Myeloid Leukemia Patients and Their Impact on the Clinical Progress
The Scientific and Research Council of Turkey
Advisor
2016-2018
Synthesis of Poly(cations) with Varying Molecular Architectures via RAFT Polymerization and In vitro Investigation as siRNA Carriers
The Scientific and Research Council of Turkey
Researcher
2015-2016
Determination of Effects of Apigenin on Chronic Myeloid Leukemia Stem Cells; Mechanistic Approach
Erciyes University
Researcher
2015-2016
Investigation of Cytotoxic Effects of Quercetin on CML Stem Cells at Molecular Level
Erciyes University
Principal Investigator
2011-2012
Apoptotic Effects of CAPE and Gossypol on Acute Lymphocytic Leukemia Cells
Turkish Society of Hematology
Principal Investigator
2010-2013
Therapeutic Potentials of Bioactive Sphingolipids in Chronic Myeloid Leukemia
Turkish Academy of Sciences
Advisor
2013-2015
Development of PEG-peptide conjugate anticancer drug carrier systems responding pH
The Scientific and Research Council of Turkey
Researcher
2014-2015
Treatment of HT-29 and HCT-116 colon cancer cell lines with mesenhcymal stem cells
Istanbul University
Advisor
2012-2014
Effect of Mesenchymal Stem Cell on Experimental Bronchiolitis Obliterans Therapy
The Scientific and Research Council of Turkey
Assistant Researcher
2012-2013
Genome Wide Expression Levels of mRNA and miRNA in Response to anti-STAT5A in Parental and Imatinib Resistant Human K562 Chronic Myeloid Leukemia Cells
Ege University
Assistant Researcher
2012-2013
Determination of Possible Synergistic Apoptotic Effects of Dexamethasone With Foxm1 Inhibitor, Siomycin A, in Acute Lymphocytic Leukemia
Dokuz Eylul University
Assistant Researcher
2012-2013
Effects of Nilotinib on Endothelial Cell Function
Dokuz Eylul University
Assistant Researcher
2012-2013
Evaluation The Effects of Gene Therapy, Ultrasound and Photobiomodulation on Orthodontically Induced Root Resorption
Erciyes University
Assistant Researcher
2012-2014
The roles of Mesenchymal Stem Cells on Experimental Allergic Rinit Therapy
Dokuz Eylul University
Principal Investigator
2009-2011
The Involvement of Ceramide Metabolizing Genes and Their Products in Docetaxel Induced Apoptosis in Human Androgen Resistant Prostate Cancer Cells
The Scientific and Research Council of Turkey
Principal Investigator
2008-2011
Multidrug Resistance Mechanisms In Chronic Myeloid Leukemia Cells Treated With Molecular Targeting Agents, Activated Signal Transduction Pathways And Reversal Of Resistance
The Scientific and Research Council of Turkey
Principal Investigator
2008-2010
Induced Cancer Signalling Pathways, Activated Cell Death Mechanisms and the roles of Ceramide Metabolising Genes on These Mechanisms in Acute and Chronic Myeloid Leukemia Cells Exposed to Resveratrol
Turkish Society of Hematology
Principal Investigator
2008-2010
The Effects of Ceramide Metabolism Genes On Apoptotic Pathways Induced By Different Anticancer Agents in Breast Cancer
Turkish Association for Cancer Research and Control
Assistant Researcher
2008-2011
Redox regulation of human p53 tumor suppressor gene activity
European Union, COST Action
Assistant Researcher
2010-2012
Monte Carlo Techniques for Biological and Chemical Reactions
TUBITAK
Turkey-Italy Bilateral Project
Assistant Researcher
2009-2011
Distraction Osteogenesis by the help of stem cells obtained from lipid tissues; An experimental study in Rabbit Tibia
Dokuz Eylul University
Prinicipal Investigator
2008-2009
Expression Analyses of Apoptotic and Drug Resistance Genes in STI571 applied parental and resistant K562 Cells
Izmir Institute of Technology
Assistant Researcher
2006-2008
Investigations and reversal of multidrug resistance mechanisms by molecular approaches in different cell lines
The Scientific and Research Council of Turkey
Assistant Researcher
2004- 2006
Investigations of Multiple Drug Resistance Mechanisms in Imatinib Mesylate Applied Chronic Myeloid Cell Lines
Middle East Technical University
Assistant Researcher
2000-2004
Investigations of Resistance Mechanisms Against Anticancer Drugs in breast Cancer and Drug Targeting
State Planning Organization
Assistant Researcher
(2000-2002)
Etermination of Expression Levels of MDR1 Gene in Blood
Middle East Technical University