PROJECTS

PROJECTS

 

POSITION & DATE

TITLE

SUPPORTED BY

Prinicipal Investigator

2015-2016

A Novel Therapeutic Approach for Ph+ Acute Lymphoblastic Leukemia; Targeting Sphingosine Kinase Signaling Pathway

Eczacibasi Holding

Prinicipal Investigator

2015-2016

Expression Levels of JAK-STAT Signaling Pathway Genes and Their Effects on Clinical Outcome in Chronic Myeloid Leukemia Patients

Guven Hospital

Prinicipal Investigator

2012-2015

Expression and Protein Levels of Bioactive Sphingolipid Genes in Newly Diagnosed and Drug-Resistant Chronic Myeloid Leukemia Patients and Their Impact on the Clinical Progress

The Scientific and Research Council of Turkey

Researcher

2015-2016

Determination of Effects of Apigenin on Chronic Myeloid Leukemia Stem Cells; Mechanistic Approach

Erciyes University

Researcher

2015-2016

Investigation of Cytotoxic Effects of Quercetin on CML Stem Cells at Molecular Level

Erciyes University

Prinicipal Investigator

2011-2012

Apoptotic Effects of CAPE and Gossypol on Acute Lymphocytic Leukemia Cells

Turkish Society of Hematology

Prinicipal Investigator

2010-2013

Therapeutic Potentials of Bioactive Sphingolipids in Chronic Myeloid Leukemia

Turkish Academy of Sciences

Advisor

2013-2015

Development of PEG-peptide drug carrier systems capable of fast drug release in endosomal compartments for more effective treatment of cancer

The Scientific and Research Council of Turkey

Researcher

2014-2015

Treatment of HT-29 and HCT-116 colon cancer cell lines with mesenhcymal stem cells

İstanbul University

Advisor

2012-2014

Effect of Mesenchymal Stem Cell on Experimental Bronchiolitis Obliterans Therapy

The Scientific and Research Council of Turkey

Assistant Researcher

2012-2013

Genome Wide Expression Levels of mRNA and miRNA in Response to anti-STAT5A in Parental and Imatinib Resistant Human K562 Chronic Myeloid Leukemia Cells

Ege University

Assistant Researcher

2012-2013

Determination of Possible Synergistic Apoptotic Effects of Dexamethasone With Foxm1 Inhibitor, Siomycin A, in Acute Lymphocytic Leukemia

Dokuz Eylul University

Assistant Researcher

2012-2013

Effects of Nilotinib on Endothelial Cell Function

Dokuz Eylul University

Assistant Researcher

2012-2013

Evaluation The Effects of Gene Therapy, Ultrasound and Photobiomodulation on Orthodontically Induced Root Resorption

Erciyes University

Assistant Researcher

2012-2014

The roles of Mesenchymal Stem Cells on Experimental Allergic Rinit Therapy

Dokuz Eylul University

Prinicipal Investigator

2009-2011

 

The Involvement of Ceramide Metabolizing Genes and Their Products in Docetaxel Induced Apoptosis in Human Androgen Resistant Prostate Cancer Cells

The Scientific and Research Council of Turkey

Prinicipal Investigator

2008-2011

 

Multidrug Resistance Mechanisms In Chronic Myeloid Leukemia Cells Treated With Molecular Targeting Agents, Activated Signal Transduction Pathways And Reversal Of Resistance

The Scientific and Research Council of Turkey

Prinicipal Investigator

2008-2010

 

Induced Cancer Signalling Pathways, Activated Cell Death Mechanisms and the roles of Ceramide Metabolising Genes on These Mechanisms in Acute and Chronic Myeloid Leukemia Cells Exposed to Resveratrol

Turkish Society of Hematology

Prinicipal Investigator

2008-2010

The Effects of Ceramide Metabolism Genes On Apoptotic Pathways Induced By Different Anticancer Agents in Breast Cancer

Turkish Association for Cancer Research and Control

Assistant Researcher

2008-2011

 

Redox regulation of human p53 tumor suppressor gene activity

European Union,

COST Action

Assistant Researcher

2010-2012

 

Monte Carlo Techniques for Biological and Chemical Reactions

TUBITAK

Turkey-Italy Bilateral Project

Assistant Researcher

2009-2011

 

Distraction Osteogenesis by the help of stem cells obtained from lipid tissues; An experimental study in Rabbit Tibia

Dokuz Eylul University

Prinicipal Investigator

2008-2009

Expression Analyses of Apoptotic and Drug Resistance Genes in STI571 applied parental and resistant K562 Cells

Izmir Institute

of Technology

Assistant Researcher

2006-2008

Investigations and reversal of multidrug resistance mechanisms by molecular approaches in different cell lines.

The Scientific and Research Council of Turkey

Assistant Researcher

2004- 2006

Investigations of Multiple Drug Resistance Mechanisms in Imatinib Mesylate Applied Chronic Myeloid Cell Lines.

Middle East Technical University

 

Assistant Researcher

2000-2004

Investigations of Resistance Mechanisms Against Anticancer Drugs in breast Cancer and Drug Targeting.

State Planning Organization

Assistant Researcher

(2000-2002)

Expression of MDR1 Gene in HL60 Cell Line Selected for Resistance to Vincristine

Middle East Technical University